Health & Medical stomach,intestine & Digestive disease

Fecal Microbiota Transplantation

Potential Adverse Events


The potential adverse events from a FMT can be related to the procedure itself or related to the infusion of another human's feces. Procedurally, both routes have their specific (mostly theoretical) risks. Colonoscopy can only be performed by a trained physician, and has a small risk of perforation or bleeding. Although our experience is that infusing feces through a duodenal tube is less invasive and less strenuous than through colonoscopy, there is a potential risk of vomiting if bowel passage is hampered. Donor feces should therefore be infused slowly. Most case series lack reporting adverse effects. In the randomized trial for CDI, no significant differences in adverse events among the three study groups were observed, except for mild diarrhea and abdominal cramping in the infusion group on the day of infusion. Transfer of infectious diseases has not been reported.

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